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DSIP crosses the blood-brain barrier freely an unusual property for a peptide of its size via a non-competitive, non-saturable passive mechanism whose physicochemical determinants (lipophilicity, charge, molecular weight, and protein-binding) are now well characterised

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This pharmacokinetic profile has made it a subject of investigation in neuroendocrinology, sleep research, and stress physiology at the laboratory level

Whitens the skin colour and also reduces the dark mark 9

2019;9:a036780